Cellular sclerosis (s. cellularis; synonym: indirect) is a chronic progressive demyelinating disease of the central nervous system, characterized by multiple foci of demyelination in the brain and spinal cord.
With cellular sclerosis, diffuse damage to the white matter of the brain and spinal cord is noted with the formation of multiple foci of demyelination. In this case, the axons of the nerve fibers are preserved, and oligodendroglia grow and fill the resulting cavities.
Clinically, cellular sclerosis is manifested by multiple neurological disorders, such as sensory disturbances, motor and coordination disorders, which are associated with damage to various parts of the central nervous system. The course of the disease is chronic and progressive with periodic exacerbations.
Treatment of cellular sclerosis includes the use of glucocorticoids, immunosuppressants and symptomatic therapy. The prognosis depends on the rate of progression of the disease.