Shaudinna Mix

Schaudinna mixture is a fixative solution used for fixing and staining cells and tissues in cytology and histology.

Composition of the mixture:

1. Ethyl alcohol - 25 ml
2. Ether - 8 ml
3. Glacial acetic acid - 5 ml

The Schaudinn mixture was developed by the German bacteriologist Fritz Schaudinn at the beginning of the 20th century. It was widely used to fix blood smears in the diagnosis of syphilis using dark-field microscopy.

Benefits of Shaudin mixture:

1. Penetrates quickly into tissues
2. Fixes cell structures well
3. Preserves the morphology of cells and microorganisms
4. Allows you to obtain good staining of the drug

Schaudinna mixture is still used as one of the classic fixatives in cytology and histology, despite the advent of more modern fixing solutions.