Chic Reaction

Chic reaction

Chick test is a diagnostic test used to detect diphtheria infection. It was developed in 1910 by the Austrian pediatrician Bela Schick (1877-1967).

The essence of the test is as follows: a diluted solution of caustic soda or caustic potassium is applied to a suspicious area of ​​the mucous membrane of the throat or nose. In the presence of diphtheria infection, fibrinous films swell and a white rim forms around them. This is a positive Chic reaction.

The reaction mechanism is due to the fact that diphtheria bacillus toxins cause tissue necrosis and fibrin deposition. Caustic soda or potassium erodes the surface layer of cells, releasing fibrin and making it visible.

Chic reaction is a fairly specific test that allows you to quickly suspect diphtheria. However, the final diagnosis must always be confirmed bacteriologically. A positive Chic reaction in itself is not indisputable evidence of the presence of diphtheria.

Thus, the Schika reaction is a classic diagnostic test in medicine, which retains its importance today. It helps doctors quickly recognize a dangerous infection and begin treatment in a timely manner.