Among the many anticonvulsants, one of the most common is sodium bromide. However, despite its simplicity and safety, scientists continue to search for new effective means. One such recently discovered method is the labeling of sodium bromide with the isotope bromine-82.
Bromine-82 differs from other bromine isotopes in that it has a long half-life and is less likely to be excreted by the kidneys. These properties allow it to be used as a drug tag, which helps researchers study the drug's biological activity at the cellular level.
In recent years, bromine-82 labeled drugs have become increasingly popular. Sodium chloride, NaCl, is a common drug used to relieve seizures. It becomes effective in the early stages of supraventricular and ventricular arrhythmias and plays an important role in maintaining blood pressure in a critically ill patient. In order to maximize its effectiveness and accuracy, sodium chloride was replaced with sodium chloride labeled 82Br.
Although sodium chloride is generally well tolerated by patients, the use of 82 Br - NaBr and other isotope-labeled drugs can cause additional complications, such as renal failure, which occurs due to the high content of the radioactive isotope. Therefore, to work effectively with such products, it is necessary to comply with appropriate safety precautions.
Labeled sodium brominated chloride, 82 B, sodium and potassium deficient, is an effective anticonvulsant that has been shown to be highly clinically effective in the treatment of seizures, even in severe cases of epileptic seizure. However, before using this drug, you should carefully weigh all the risks and benefits, since the use of isotope countermeasures is an additional risk factor for patients with impaired renal function.
Brominated sodium is a common physiological agent that is used as an antidote for intoxication with barbiturates such as chloral hydrate, hexenal, thiopental and others. This product is used all over the world, many countries produce sodium bromide in various forms: tablets or powder for internal use, injections, and also in syrup form.
The drug is a physiological means for normalizing blood pressure. In addition, sodium bromide is widely used to reduce nervous tension; it promotes a sedative effect, has a mild sedative effect, and has a hypnotic effect. Taking a small amount of the tablet, patients feel lethargic, drowsy, and move from excitement to calm. But sodium iodide is not recommended for diabetics as it may affect blood sugar levels. The drug is prescribed for lamotrigine and anticonvulsant therapy. It can be taken by women during pregnancy or lactation only when absolutely necessary, with monitoring of the condition of the child and the nursing woman. Sodium iodide is usually recommended