Stercobilin (Stercobilm)

Stercobilin

Stercobilin is a brownish-reddish pigment that is formed during the metabolism of the bile pigments biliverdin and bilirubin. In turn, these pigments are products of the breakdown of hemoglobin.

The formation of stercobilin occurs in the intestine under the action of bacterial enzymes that reduce bilirubin to stercobilinogen. Stercobilinogen is then oxidized to stercobilin.

Normally, a small amount of stercobilin is excreted from the human body in feces, giving it its characteristic brown color. Also, small amounts of stercobilin can be excreted by the kidneys in the urine.

An increased content of stercobilin in urine and feces may indicate diseases of the liver and biliary tract, accompanied by impaired bilirubin metabolism.

Stercobilin is a brownish-red pigment that is formed during the metabolism of biliverdin and bilirubin. These two pigments are formed from hemoglobin and are breakdown products of red blood cells. Stercobilin is excreted in urine and feces and is an important indicator of the functioning of the liver and gastrointestinal tract.

Stercobilin is one of the most important components in the diagnosis of various diseases of the gastrointestinal tract and liver. For example, changes in stercobilin levels in the blood may indicate the presence of liver disease such as cirrhosis or hepatitis. In addition, stercobilin levels can be used to assess the effectiveness of treatment for liver and gastrointestinal diseases, as well as to monitor the condition of patients after liver or gastric surgery.

To determine the content of stercobilin in urine or feces, a special analysis is used, which is called a coprological study. This analysis allows you to evaluate the functioning of the liver, gastrointestinal tract and other organs, as well as identify the presence of inflammatory processes or other diseases.

In general, stercobilin plays an important role in the diagnosis and treatment of liver and gastrointestinal diseases. Its content in urine and feces can be used to assess health status and the effectiveness of treatment.

Definition

Stercobilin is a brownish-red pigment that is formed in the human body from biliverdin (a metabolite of bilirubin) during metabolism. The formation of stercobilinogen occurs in the liver, where biliverdin is converted to stercobilanine. Stercobilinanine is then released through the intestinal epithelium along with feces into the human body through the kidneys and bile ducts. Thus, the pigment stercobillin takes an active part in health processes.

Biochemistry

Stercobilinobin is obtained from biliverdins and bilirubins by decomposing these pigments with water and acetates containing Fehling's reagent. In this case, iron loss occurs (yellow-green iron salts precipitate). After this, stercobylnogen, under the influence of bile cations, turns into an insoluble but durable pigment. The latter circulates in the plasma for 20 minutes, after which it dissolves and remains in water. The main mechanisms for removing stercobilinolamine from liver are blood and glomerular filtration, partially excreted by the kidneys. Excreted primarily through feces, and is found in urine only in some patients.

During the day, about 180 mg of bilirubin pigments are formed, 2 g oxidized to stercobinogens. An hour after the release they beat me