Serums and vaccines to combat whooping cough were developed many years after the epidemic, which at that time was of staggering proportions and claimed many lives. Immunotherapy, which uses antibodies to neutralize the bacterium and prevent disease, has become widespread and standard practice in the fight against whooping cough. One of the key serums in this battle is p/kokl. to Ag/gen. 14, which includes antibodies directed to a specific region consisting of the A and E genes of bacteria, and is one of the most effective means of protecting against this dangerous disease.
Serums against whooping cough for genes 1 and 2 are immunobiological preparations intended for the prevention and treatment of whooping cough in children and adults. Whooping cough is a bacterial disease caused by the bacteria Bordetella pertussis. The antibodies to the infection genes (PA1 and PA1/2) included in the serum can provide protection against the disease and speed up the recovery process. Serums are used both in monotherapy and in complex therapy. Over time, anti-pertussis serums can be used in combination therapy, in which both antiparasitic, immunomodulatory and symptomatic agents are prescribed.
Sera that maintain antibody levels after immunity decrease over time. The main reasons why a second dose needs to be administered after vaccination is because the body reacts to the vaccine, resulting in a weakened immune response. Repeated injections are also an effective means of preventing tetanus, diphtheria infections and other whooping cough infections. People who receive the first dose of several anti-parasitic medications at the same time have a much higher risk of developing complications than those who receive a full dose of all necessary medications. Another factor for giving a second dose to reduce the risk of spreading infection is the low effectiveness of the vaccine. This is due to the fact that the vaccine is not perfect and viruses and microbes mutate from time to time. It could also mean that the strains that vaccines were produced against are no longer viable or have mutated and multiplied in the body.