Tamoxifen (Tamoxifen)

Tamoxifen is a drug that is used to treat breast cancer in women. It works by binding to hormone receptors on tumor cells, which inhibits their activity and prevents tumor growth.

One of the side effects of taking tamoxifen is flushing, which can cause discomfort in some women. Pain in the tumor area and increased calcium levels in the blood are also possible. However, these side effects are rare and usually not serious.

Research is currently underway into the possible use of tamoxifen as a preventative treatment for women at risk of developing breast cancer. This can help prevent the development of the disease and improve the quality of life of patients.

The trade name of the drug is Nolvadex. It is available in tablet form and is administered orally. Before starting to take tamoxifen, you should consult your doctor and undergo an examination to ensure that there are no contraindications to its use.

Tamoxifen is a drug used to treat breast cancer and other cancers associated with hormonal imbalances.

Tamoxifen is an anti-estrogen that blocks the action of estrogen on tumor cells, thereby inhibiting their growth and development. It binds to estrogen receptors present on the surface of tumor cells and blocks their effect on these cells.

One of the side effects of using tamoxifen is flushing of the face. This may manifest as skin redness, fever, sweating and palpitations. Pain in the area of ​​the tumor and increased levels of calcium in the blood (hypercalcismia) may also occur.

Research is currently being conducted to examine the possibility of using tamoxifen in women at risk of developing breast cancer. This helps prevent the development of cancer and improve the quality of life of such women.

The trade name for tamoxifen is Nolvadex. It comes in a variety of forms, including tablets, capsules, and topical cream.

Tamoxifen is an antiestrogenic drug that binds to estrogen receptors on the cell membrane, having a blocking effect on the effects of both endogenous and exogenous estrogens. The maximum effect develops after 3–4 weeks. after starting therapy. After completion of therapy, the effectiveness of its use gradually decreases (on average after 5 weeks). In breast cancer, the therapeutic effect is associated with a direct effect on tissue culture under experimental conditions. Although there are no serious studies comparing the use of tamoxifin and other drugs with a similar mechanism of action in the treatment of breast cancer, and there is not enough data to date to confirm or refute the effectiveness of this drug in breast cancer. Hormone therapy is far from the only way to treat cancer; even benign tumors can refuse it. The studies were conducted with only 1 group of patients. The development of cancer is likely to occur in the future, so you should not use hormones until cancer is detected. The results were assessed only by observing 195 patients for 22 years. More than half of them were eventually diagnosed with another tumor disease (for example, ovarian, cervical or pancreatic). The likelihood of relapse has increased significantly compared to the baseline. With further observation, after 63 years (maximum for 28 years), the results differ only statistically - all incidence indicators decreased significantly: retroperitoneal lymphoma (recognized as one of the most harmful consequences of the use of hormonal anticancer drugs), and a very low percentage of the development of osteoporosis and myocardial infarction. The tablets are taken orally (without chewing and with water) and are usually taken during or immediately after meals, at the same time, regardless of meal time. They are recommended to be taken every day at a fixed time. If a woman took a break from taking the drug during the day for more than 4 hours, then she needs to take the next dose a little earlier than usual.