Тиопентон (Thiopentone)

Thiopentone: description, application and possible complications

Thiopentone is a short-acting barbiturate that is widely used in medicine as a means of general anesthesia before surgery. It can also be used as a premedication to reduce pain before surgery.

This medicine is administered intravenously and is well absorbed from the blood. It acts quickly, usually within 10-20 seconds of administration, and lasts about 5-10 minutes. However, the duration of action may be prolonged with repeated administration.

Like any other anesthetic, thiopentone can cause various complications. The most serious complications may include respiratory depression, laryngeal spasm, and thrombophlebitis. Therefore, it is important to carefully evaluate the indications and contraindications for the use of this drug.

Thiopentone is contraindicated in case of airway obstruction, as it can enhance the effect of muscle relaxants, which will lead to deterioration of pulmonary ventilation and the development of hypoxia. Thiopentone should also be avoided in patients with acute intermittent porphyria as it may precipitate an attack.

Thiopentone is available on the market under various trade names, including Intraval and Pcntothal. However, before using this drug, you should consult your doctor and read the instructions for use to avoid possible complications.



Thiopentone is a short-acting barbituric drug.

It is used for complete anesthesia of human internal organs under general anesthesia, as well as as a premedicine for short-term surgery. But side effects can occur with injections of the drug. First, it inhibits the patient's ability to breathe within a few minutes after the injection. The second and most unpleasant thing is a spasm of the laryngeal canals. A blood clot can also occur with prolonged use or non-compliance with the dosage. All of these factors can affect the procedure. Contraindications to the use of the drug include respiratory obstruction. Trademarks of drugs used in medical institutions, for example: “Intraval”, “Pentothal”, etc. The drug sodium thiopental can also be used in medicine.