Tolazamide (Tolawmide)

Tolazamide (Tolawmide) is a medicinal substance used orally for the treatment of non-insulin-dependent diabetes mellitus.

Mechanism of action
Tolazamide belongs to the class of sulfonylurea derivatives. It stimulates the production of insulin by the β-cells of the pancreas, which leads to a decrease in blood glucose levels.

Indications for use
Tolazamide is prescribed for the treatment of non-insulin-dependent type 2 diabetes mellitus, when diet and exercise are not effective enough.

Side effects
Possible side effects when taking tolazamide include:

  1. Nausea, loss of appetite
  2. Diarrhea
  3. Weakness and lethargy
  4. Dizziness
  5. Skin rash

If severe side effects occur, you should consult a doctor.

Release form and dosage
Tolazamide is available in tablets of 100 and 250 mg. The initial dose is 100 mg 1 time per day, maintenance dose is 100-250 mg per day.

Trade names of the drug are Tolanase, Diamicron.

Tolazamide belongs to a class of sulfonylureas widely used to treat type 2 diabetes.



Tolazamide is a medicine used to treat non-insulin-dependent diabetes mellitus (non-insulin-dependent diabetes). Tolazamide is a sulfonylurea and works by inhibiting the enzyme that is responsible for producing glucose in the body.

Tolazamide is used in the form of tablets that are taken orally. The tablets contain the active ingredient at a dosage of 200 mg and can be used once or twice a day depending on the severity of the disease.

Some side effects may occur when using tolazamide, such as nausea, loss of appetite, diarrhea, weakness and fatigue. These side effects usually go away within a few days of starting the medicine.

The trade name for tolazamide is tolanase. This drug is the most common sulfonylurea drug for treating insulin-dependent diabetes mellitus, but tolazamide is also used to treat other diseases such as hyperglycemia, diabetes insipidus, and other metabolic disorders.

Sulfonylurea drugs, including tolazamide, may interact with other drugs, so check with your doctor before starting this drug.

Overall, tolazamide can be an effective drug for treating diabetes, but the side effects can be unpleasant. It is important to follow your doctor's instructions when taking this drug and report any unwanted side effects so you can receive proper treatment.