Transferrin, Siderophilin

Transferrin, also known as Siderophilin, is a plasma glycoprotein that plays an important role in iron homeostasis in the body.

Transferrin binds ferrous ions (Fe2+), forming stable insoluble complexes, which prevents the toxic effects of excess free iron. Moreover, the binding is reversible - transferrin can both capture and release iron depending on the needs of the cells.

Due to the ability to bind to transferrin receptors on the surface of cells, this protein ensures the transport and delivery of iron to the cells that need it - bone marrow red blood cells, hepatocytes, and cells of the immune system.

Thus, transferrin plays a vital role in the body - it is responsible for maintaining normal levels of iron in the blood and its distribution between various tissues and cells. Disturbances in the functioning of this protein lead to the development of iron deficiency anemia or hemosiderosis.

Transferrin is a glycoprotein found in human blood plasma. It plays an important role in the transport of iron in the body. Transferrin binds iron and transports it through the bloodstream to organs and tissues that need this element.

Transferrin consists of two subunits - alpha and beta chains. The alpha chain contains many glucose residues that form a hydrated complex with iron ions. This allows transferrin to bind large amounts of iron and transport it through the blood.

Siderophilin is another blood glycoprotein that can also bind iron. It differs from transferrin in that it does not contain glucose residues and cannot bind such large amounts of iron. In addition, siderophilin does not transport iron through the blood, but serves to store it in cells.

Thus, transferrin and siderophilin play an important role in iron metabolism in the human body. Transferrin transports iron from organs and tissues where it is needed to places where it can be used, and siderophilin stores iron in cells when it is not needed for exchange.

Transferrin is a protein molecule that performs the function of transporting iron in the human body. This protein is secreted by the liver and produced in the spleen. The main functions of transferrin are: - Reversible binding of iron; - Transportation of iron through the blood plasma throughout the body. Transferrin is present in the blood plasma of healthy people in concentrations up to 500 μg/l. Typical sizes of a protein molecule