Transfusion Reaction

Transfusion Response: Understanding and Managing

During medical procedures, such as intravenous fluids, a transient condition known as a transfusion reaction can sometimes occur. This phenomenon is characterized by general malaise, chills and fever, and may occur as a result of infusion of blood or blood substitutes. In this article we will look in more detail at this reaction, its causes, symptoms and possible measures to prevent and manage it.

A transfusion reaction is the body's response to the introduction of foreign material, such as blood or its components. It can occur in varying degrees of severity, from mild to severe, and requires immediate response from medical personnel.

One of the main causes of transfusion reaction is a mismatch between the blood of the donor and recipient. This may be due to incompatibility of blood groups or the presence of antibodies in the recipient's blood that react with components of the donor blood. Other possible causes include improper storage or transfusion of blood, and contamination of the blood with microorganisms.

The main symptoms of a transfusion reaction are general malaise, chills and fever. Patients may also experience headaches, chest pain, rapid heartbeat, and difficulty breathing. In some cases, a transfusion reaction can lead to more serious complications such as allergic reactions, thromboembolism, or kidney damage.

To prevent a transfusion reaction, it is important to carefully select the donor's blood, taking into account the compatibility of blood groups and the presence of antibodies. Strict blood storage and transfusion protocols must also be followed to avoid contamination or improper handling. If a transfusion reaction is suspected, the fluid infusion should be stopped immediately and medical attention should be sought.

If a transfusion reaction occurs, it is important to promptly manage the patient's condition. Treatment may include stopping the infusion, symptomatic therapy to relieve symptoms, and maintaining vital functions. In some cases, antihistamines, steroids, or other medications may be needed to control allergic reactions.

In conclusion, a transfusion reaction is a transient condition of the body that can occur during intravenous infusion of fluids, especially blood or blood components. It is important to carefully select donor blood and follow blood storage and transfusion protocols to prevent a reaction. If a reaction occurs, stop the infusion immediately and seek medical attention. Timely management of the patient's condition and adequate treatment play an important role in preventing serious complications. Transfusion reaction is a serious medical condition, but with the right approach and precautions, its risks can be minimized.



Transfusion reactions (TR) are one of the most common complications of blood transfusion.

This emergency and potentially life-threatening condition is characterized by the rapid development of an acute tissue reaction that occurs to the introduction of a foreign substance or material for the transfusion of fluids. The cause of TR is the lack of physiological compatibility between recipient and donor tissues. TR can lead to serious complications such as shock, circulatory failure, organ damage, infection, etc.

One of the main methods of preventing TR is the systematic selection of the correct biological type of antigen of the transfused components from the individual blood donor and recipient. However, in some cases, even with high quality blood products, TR may still occur. In this case, trans