Transglutaminase

Transglutaminase (TG) is an enzyme that plays an important role in the biochemical processes of the human body. It is part of a family of enzymes known as transaminases and has the function of catalyzing a reaction that results in the binding of various protein molecules.

TG is widely distributed in the body and can be found in many tissues, including skin, bone, muscle, liver and blood. It plays an important role in blood clotting, regulating the immune system and repairing damaged tissue.

One of the important properties of TG is its ability to bind amino acids inside protein molecules, creating so-called cross-links. This makes it possible to improve the mechanical properties of proteins, making them stronger and more resistant to damage.

However, if the level of TG in the body becomes too high, it can lead to various diseases such as celiac disease, Parkinson's disease and Hunt's syndrome. In celiac disease, for example, the human immune system reacts to cross-talk created by TG, leading to intestinal damage and dysfunction.

Even though TG is an important element in the body, its levels should always be under control. Studying the work of this enzyme may lead to the development of new methods for treating diseases associated with its activity. For example, some studies have shown that TG inhibition may be an effective treatment for celiac disease.

In general, transglutaminase is an important component of biochemical processes in the human body. Its study can help uncover new disease mechanisms and develop effective treatments.