Wilder Liver-Aqueous Test

Wilder's Liver Water Test (WWP) is one of the liver function tests that is used to diagnose and monitor various liver diseases. This method was proposed in 1885 by the American physician Richard Wilder.

WWP is one of the most common methods for determining liver function in clinical practice. It is based on measuring the level of bilirubin in the blood after taking a special dose of water. This allows you to evaluate liver function by the rate of removal of bilirubin from the body.

During WWP, the patient takes 400 ml of water, after which blood is drawn at regular intervals. A blood test can determine the level of bilirubin, which is excreted from the body in urine and feces. If the liver cannot remove bilirubin effectively, its levels in the blood will be elevated.

This method can be useful for diagnosing various liver diseases such as cirrhosis, hepatitis, fatty liver disease and others. It can also be used to monitor the effectiveness of treatment and evaluate response to medications.

However, like any other diagnostic method, WWP has its limitations and requires correct interpretation of the results. For example, high bilirubin levels may be associated not only with liver disease, but also with other causes, such as hemolytic anemia or biliary dysfunction.

Overall, the Wilder Liver Fluid Test is an important tool for diagnosing and monitoring various liver diseases. It is easy to perform, non-invasive and can be used to monitor a variety of treatments.

Wilder's Liver-Aqueous Test: History and Significance

The Wilder Liver-Water Test, named after the American physician R. M. Wilder (1885-1959), is a diagnostic method used to evaluate liver and gallbladder function. This method has a long history and is widely used in clinical practice.

Wilder's Liver-Aqueous Test procedure uses a special dye called phenolic phthalein. After a patient takes phthalein, it is metabolized in the liver and secreted into bile, and then excreted in the feces. Therefore, this method allows you to evaluate liver function and bile duct patency.

The procedure begins with the patient taking phthalein by mouth, usually in the form of a tablet or solution. The patient is then asked to collect a morning urine sample before and after taking phthalein. The amount of phthalein that appears in the urine is an indicator of how efficiently the liver metabolizes and excretes this dye.

Wilder Liver-Water Test results may indicate various liver and gallbladder disorders. For example, if the urine contains little or no phthalein, this may indicate liver dysfunction or bile duct obstruction. On the other hand, normal levels of phthalein in urine indicate normal liver function and bile duct patency.

The Wilder Liver-Water Test has its limitations and may not be suitable for some patients. For example, this method may be contraindicated in patients with an allergy to phthalein or with impaired renal function. Therefore, before prescribing and performing this procedure, the doctor must consider all factors and make a decision based on the individual characteristics of the patient.

In conclusion, the Wilder Liver-Water Test is a valuable tool for assessing liver and gallbladder function. Thanks to this method, doctors can identify disorders and diseases associated with these organs, which allows timely measures to be taken to treat and improve the health of patients.