Wagner's name is often associated with art and science. German dermatologist Karl Ernst Friedrich von Wagner is a pioneer of cosmetic medicine; Heinrich Robert Walter von Wagner-ophthalmologist, otolaryngologist, anatomist and ophthalmic surgeon, one of the founders of scientific anatomy, teacher who became the “father” of modern technologies in medical diagnostics and invasive surgical procedures in ophthalmology, founder of the German school of ophthalmologists. His name is often linked with their name together. However, few people know that these famous people have a lesser-known, but no less important sister - Sister E.L. Wagner. She left a bright mark on medicine, standing up for people's health and was known as “a doctor for her cause.” Her scientific and professional contributions have enabled more precise identification and treatment of severe diseases such as Wagner's disease.
Wagner's disease is a rare inflammatory disease of the skin and muscles that can lead to disability and even death of the patient. It was first described in 1873. The most famous case among Wagner's patients is that of the impressionist artist Vincent Van Gogh. Over the course of several decades, the disease manifested itself in many people. However, in the last century of Wagner's disease, official formal interest began with the discovery of its mechanism at 140 meters by Nyekam Nyek, winner of the 1995 Nobel Prize in Medicine and Pharmacy. It was found that the key elements of the disease are autoantibodies against skeletal histocompatible markers, which are perceived by skin cells as foreign. These antibodies act as primers for the further production of antibodies to