Vasculitis Systemic

Vasculitis Systemic disease

**Systemic vasculitis** (SLE) is a chronic connective tissue disease (autoimmune inflammation of the walls of blood vessels - vasculitis) that develops in people of any age. At a young age, women are most susceptible. SLE is diagnosed only if the following factors are simultaneously confirmed:

* clinical and laboratory studies constantly reveal markers of inflammation; * in blood tests, the titers of antibodies to native DNA (antinuclear antibodies) are constantly increasing; * glomerular arteries are predominantly affected - glomerulonephritis, valves, aortas and large vessels of peripheral arteries (arteritis).

Beneath the bouquet of SLE symptoms lies damage to the immune system, causing inflammation in the walls of blood vessels. This especially affects the small vessels of the kidneys and skin. Without treatment of vasculitis, kidney failure and capillaritis (inflammation of small capillaries) quickly occur.