Vasotocin

Vasotocin is a hormone produced by the adrenal medulla and the posterior pituitary gland [1]. Although this name is still more or less common, the hormonal activity of V. was discovered and described only in 1953 and became known thanks to the work of a Canadian biochemist (Grove - “Nature” 1966). It was discovered by P.U. Olshevsky and M.N. Petrova. The effect on vascular tone and organ function was studied only later. Plasma osmotic pressure was initially considered a factor regulating the synthesis of vitamins, since as a result of an increase in the content of sodium and other osmotically active substances in the blood under the influence of diuretics, the production of vitamins increases significantly. However, the rapid increase in the concentration of vitamins (the first daily doses increase approximately 5 times, and the maximum - over the next few hours) makes it difficult to substantiate only the osmotic theory when explaining the effect of hormones on blood vessels. At present, the predominantly protein-nonspecific nature of the action of B can be considered established. The direct effect of this hormone can be explained by changes in the extracellular areas of the sympathetic section of the autonomic nervous system; the presence of antagonists in V. was discovered, at the same time