Viferon 2

Country of origin: Russia
Pharm-Group: Antiviral - interferons

Manufacturers: Business Consulting Investment (Russia)
International name: Interferon alpha
Synonyms: Viferon 1, Viferon 3, Wellferon, Human leukocyte Interferon, Recombinant human interferon alpha-2, Recombinant human interferon d/in dry (Rekolin), Reaferon, Reaferon-EC
Dosage forms: suppositories 500000IU
Ingredients: Recombinant human interferon alpha.

Indications for use: Hairy cell leukemia, chronic myeloid leukemia, viral hepatitis B, active viral hepatitis C, primary (essential) and secondary thrombocytosis, transitional form of chronic granulocytic leukemia and myelofibrosis, multiple myeloma, kidney cancer; AIDS-related Kaposi's sarcoma, mycosis fungoides, reticulosarcoma, multiple sclerosis, prevention and treatment of influenza and acute respiratory viral infection.

Contraindications: Hypersensitivity, severe heart disease (including a history), acute myocardial infarction, severe dysfunction of the liver, kidneys or hematopoietic system, epilepsy and/or other disorders of the central nervous system; chronic hepatitis against the background of decompensated cirrhosis of the liver; chronic hepatitis in patients receiving or recently receiving immunosuppressant therapy (with the exception of short-term pre-treatment with steroids). Restrictions on use: Pregnancy, breastfeeding (breastfeeding should be stopped), childhood.

Side effects: Lethargy, fever, chills, loss of appetite, muscle pain, headache, joint pain, sweating, nausea, vomiting, changes in taste, dry mouth, weight loss, diarrhea, abdominal pain, constipation, flatulence, increased peristalsis, heartburn, liver dysfunction, hepatitis, dizziness, visual disturbances, ischemic retinopathy, depression, drowsiness, impaired consciousness, nervousness, sleep disturbance, allergic skin reactions (rash, itching).

Interaction: Interferes with the metabolism of cimetidine, phenytoin, warfarin, theophylline, diazepam, propranolol.

Overdose: No information.

Special instructions: Combinations with drugs acting on the central nervous system and immunosuppressants should be avoided. Throughout the course, it is necessary to monitor the content of blood cells and liver function. To mitigate side effects (flu-like symptoms), simultaneous administration of paracetamol is recommended.

Literature: Encyclopedia of Medicines 2004.