Country of origin - United States of America, Tallinn Pharmaceutical Plant Estonia
Pharm-Group - Cyanocobalamin group (vitamin B12)
Manufacturers - General Pharma Inc. (United States of America), Tallinn Pharmaceutical Plant (Estonia)
International name - Cyanocobalamin
Synonyms - Bartel drugs vitamin B12, B12 Ankerman, Dodex, Neurobene, Cyanocobalamin
Dosage forms - tablets 100 µg, solution for injection 500 µg, solution for injection 200 µg
Composition - Active ingredient - Cyanocobalamin.
Indications for use - Chronic anemia occurring with vitamin B12 deficiency (Addison-Birmer, alimentary macrocytic), in the complex treatment of anemia - iron deficiency, post-hemorrhagic, aplastic, caused by toxic substances and drugs, myelosis, traumatic injuries and inflammatory processes of peripheral nerves (wound , radiculoneuritis, neuritis, neuralgia, causalgia, phantom pain), amyotrophic lateral sclerosis, encephalomyelitis, multiple sclerosis, diabetic neuropathy, cerebral palsy, Down's disease, skin diseases (psoriasis, photodermatosis, dermatitis herpetiformis, neurodermatitis), traumatic bone injuries and conditions after surgical operations on the musculoskeletal system with slow bone consolidation, acute and chronic hepatitis, liver cirrhosis, radiation sickness. For prophylactic purposes - when prescribing biguanides, para-aminosalicylic acid, high doses of vitamin C, for pathologies of the stomach and intestines that prevent normal absorption of the vitamin (resection of part of the stomach, small intestine, Crohn's disease, celiac disease, sprue).
Contraindications - Hypersensitivity, hypercoagulation (including in acute thrombosis), erythremia, erythrocytosis.
Side effects - Headache, dizziness, agitation, pain in the heart, tachycardia, allergic reactions (urticaria).
Interaction - Pharmaceutically (in one syringe) incompatible with solutions of vitamins, B1 and B6 (cobalt ion contributes to the destruction of other vitamins). Increases the likelihood of allergic reactions caused by vitamin B1.
Overdose - No data available.
Special instructions - During treatment, blood patterns and coagulation should be regularly monitored.
Literature - Encyclopedia of Medicines 2003