Vitamin B6: functions in the body, indications for use and contraindications
Vitamin B6 (pyridoxine) is one of the most important B vitamins. It plays an important role in many biochemical processes in the human body, such as amino acid metabolism, hemoglobin synthesis, the functioning of the nervous system, immune system and others. In this article we will look at the main functions of vitamin B6, indications for its use and contraindications.
Functions of vitamin B6 in the body
Vitamin B6 is a cofactor for many enzymes involved in amino acid metabolism. It is also necessary for the synthesis of certain neurotransmitters such as serotonin, norepinephrine and dopamine, which regulate mood and behavior. Vitamin B6 also plays an important role in the synthesis of hemoglobin, the protein that transports oxygen in the blood.
Indications for use
Vitamin B6 is used to treat various diseases and conditions, such as:
- B6-hypovitaminosis (vitamin B6 deficiency)
- Toxicosis of pregnant women
- Sideroblastic anemia
- Leukopenia (decrease in the number of white blood cells in the blood)
- Diseases of the central nervous system (parkinsonism, chorea minor, Little's disease, radiculitis, neuritis, neuralgia, Meniere's disease)
- Sea and air sickness
- Atherosclerosis
- Diabetes
- Seborrheic and non-seborrheic dermatitis
- Herpes zoster
- Neurodermatitis
- Psoriasis
- Exudative diathesis
- Use of drugs from the isoniazid group.
Contraindications and side effects
Vitamin B6 has several contraindications and may cause some side effects. Hypersensitivity is a contraindication to its use. Restrictions on use include gastric and duodenal ulcers.
Side effects may include allergic reactions and increased stomach acid.
Interaction and overdose
Vitamin B6 may interact with some medications. It may weaken the antiparkinsonian activity of levodopa and reduce the effectiveness of isoniazid, cycloserine and penicillamine.
There is no data on an overdose of vitamin B6. However, with long-term use of large doses, it may cause some unwanted effects such as neurological disorders, nausea, vomiting, diarrhea, headache and seizures. The recommended daily dose for adults is about 1.3-1.7 mg.
conclusions
Vitamin B6 plays an important role in many biochemical processes in the human body. It is used to treat various diseases and conditions such as B6 hypovitaminosis, toxicosis of pregnancy, anemia and diseases of the nervous system. However, vitamin B6 has contraindications and may cause side effects, so it should be used only as prescribed by a doctor and in accordance with the recommended dosage.