Vitrum plus vitamin C
Country of origin: United States of America
Pharm-Group: Ascorbic acid group (vitamin C)
Manufacturers: Unipharm Inc. (United States of America)
International name: Ascorbic acid
Synonyms: Additiva Vitamin C, Asvitol, Ascorbic acid, Ascorbic acid, Ascorbic acid (Vitamin C), Ascorbic acid-UBF, Bartel drugs vitamin C, Bartel drugs vitamin C chewable with orange flavor, Vitamin C, Vitamin C "Dinosaurs", Vitamin S-Roche, Vitamin C EPA, Cevit, Cebion, Citrabioflavin
Dosage forms: lemon effervescent tablets 1g, orange effervescent tablets 1g
Ingredients: Active ingredient - Ascorbic acid.
Indications for use: Hypovitaminosis C, hemorrhagic diathesis, capillary toxicosis, hemorrhagic stroke, bleeding (nasal, pulmonary, uterine, etc.), infectious diseases, intoxication, alcoholic and infectious delirium, acute radiation sickness, post-transfusion complications, liver diseases (Botkin's disease, chronic hepatitis and cirrhosis), gastrointestinal tract (achilya, peptic ulcer, especially after bleeding, enteritis, colitis, helminthiasis), cholecystitis, adrenal insufficiency (Addison's disease), sluggishly healing wounds, ulcers, bone fractures, dystrophy, physical and mental overload, pregnancy and lactation, hemosiderosis, melasma, erythroderma, psoriasis, chronic common dermatoses.
Contraindications: Hypersensitivity, thrombophlebitis, tendency to thrombosis, diabetes mellitus.
Side effects: Irritation of the gastrointestinal mucosa (nausea, vomiting, diarrhea), arterial hypertension, metabolic disorders, inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glycosuria) and glycogen synthesis, reduces capillary permeability and deterioration of tissue trophism, thrombocytosis, hyperprothrombinemia, thrombus formation, erythrocytopenia, neutrophilic leukocytosis, myocardial dystrophy, damage to the glomerular apparatus of the kidneys, allergic reactions (including anaphylactic shock); with long-term use, the formation of urinary stones, disturbances in the metabolism of zinc and copper, increased excitability of the central nervous system, sleep disturbance, and the development of microangiopathies.
Interaction: Increases blood concentrations of salicylates (increases the risk of crystalluria), ethinyl estradiol, benzylpenicillin and tetracyclines, reduces oral contraceptive use. Reduces the anticoagulant effect of coumarin derivatives. Improves the absorption of iron preparations in the intestines.
Overdose: No data available.
Special instructions: During long-term treatment, monitoring of renal function, blood pressure and glucose levels is necessary (especially when prescribing high doses). Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminase activity, LDH).
Literature: Encyclopedia of Medicines 2003