Lupus Erythematosus Systemic

Introduction

Lupus erythematodes is a complex, multifactorial inflammatory disease that affects various organs and systems of the body. It is the most common systemic autoimmune disease, characterized by a chronic, relapsing course and affecting various organs, including the skin, joints, heart, lungs, kidneys and central nervous system.

1. Etiology This part of my article will be devoted to a description of the known mechanisms and assumptions about the causes of lupus.

There are many theories that try to explain the cause of systemic lupus erythematosus, but there is still no generally accepted theory explaining the causes of this disease. Lupus erythematosus still amazes scientists around the world, as its etiology remains unclear. It is assumed that the disease may have a hereditary connection, and its occurrence may be associated with exposure to external factors. It has also been suggested that the immune system may play a central role in the development of systemic lupus erythematosus. In addition, this disease can also be caused by viral diseases such as hepatitis B retrovirus or Epstein-Barr virus, which is associated with the development of autoimmune diseases such as lupus erythematosus and multiple sclerosis. However, at the moment there is no clear answer to the question of whether this pathogen is the cause of this disease

2. Clinical picture

The clinical manifestations of systemic lupus erythematosus vary and may vary from patient to patient. One of the most common manifestations of the disease is eczematous dermatitis, accompanied by periodic outbreaks of erythema on the face and other parts of the body. There may also be rashes on the torso and limbs, dry skin, changes in the nail plate, and even bleeding. Typical connective tissue lesions in the form of arthritis, myocarditis, vasculitis and capillary disorder are also observed, including redness and swelling of the skin, changes in nail color, thinning of the nail plate and bruising.

3. Diagnostics