A biopsy is a tissue sample removed from the patient’s body by biopsy (instrumental or intraoperative). This term is used to refer to any tissue sample that is a material for scientific research. In particular, biopsies are used in the study of hereditary diseases, in the diagnosis of viral hepatitis, HIV infection, oncology and many other diseases. A biopsy is a diagnostic method, the essence of which is to remove a small fragment of any tissue from the body for further research into the cause of the disease. To obtain a biopsy sample, medical instruments such as a needle, a syringe with a thin tube at the end, scissors, or special surgical equipment are used. Moreover, the biopsy can be three-level and, according to the characteristics of its execution, is divided into two more types: Open