Parapoliomyelitis disease

Incidence of paralytic poliomyelitis and vaccine-associated paralytic poliomyelitis (VAP) among the Russian child population for the period from 2003 to 2010. can be assessed as low - 0.44±0.07 cases per 1 million population and 0.67±0.14 cases per 1 thousand child population, respectively. At the same time, there are significant territorial differences in the incidence rate, the highest incidence was recorded in the Far East, the maximum rates were noted in the Khabarovsk Territory - 32.53, and the Sakhalin Region - 49.25. Indicators of infectious morbidity with OPV remain at an unstable level, which is determined both by the level of detection of another combined form of polio combined with vaccine-active polio, and by the level of timely immunological monitoring of population immunity to OPV. In almost all regions, the presence of outbreaks with infected material has been identified. It should be noted that throughout the entire period, the number of domestic IPV entering the territory of the Russian Federation exceeded the volume of supplied vaccines against MPV (in a 26-fold and 8-fold ratio, respectively).

The frequency of detection of the vaccine strain, both on a nationwide scale and in individual regions, depends not only on the adopted immune policy, but also on