Abaktal

Abaktal: use, dosage, side effects and contraindications

Abactal (international name - pefloxacin) is an antimicrobial drug from the group of fluoroquinolones used to treat infections of various localizations. The drug is produced by several pharmaceutical companies, including in Russia and Slovenia.

Dosage forms of Abaktal include 400 mg film-coated tablets, 400 mg film-coated tablets and 400 mg/5 ml injection solution. The active ingredient is pefloxacin.

Abaktal is effective in the treatment of infections of the upper and lower respiratory and urinary tracts, infections of the skin and soft tissues, epididymitis, otitis, prostatitis, gonorrhea, chancroid, inflammatory diseases of the pelvic organs in women, cholecystitis, cholangitis, gallbladder empyema, intra-abdominal abscesses, peritonitis , septicemia, infective endocarditis, meningitis, osteomyelitis, infectious arthritis; and also for the prevention of surgical infection.

However, Abaktal has a number of contraindications, including hypersensitivity, hemolytic anemia associated with deficiency of glucose-6-phosphate dehydrogenase, cerebral atherosclerosis, epilepsy, impaired liver and kidney function, pregnancy, breastfeeding and children under 15 years of age.

During the use of Abaktal, side effects may occur, such as nausea, vomiting, diarrhea, abdominal pain, myalgia, arthralgia, tendinitis, headache, dizziness, weakness, insomnia, tremor, convulsions, tachycardia, thrombocytopenia, neutropenia, photosensitivity, skin hyperemia , skin itching and urticaria.

It is important to consider the interaction of Abaktal with other drugs. For example, Abaktal potentiates the effect of anticoagulants, increases the plasma concentration and half-life of theophylline, probenecid prolongs elimination, antacids impair absorption in the gastrointestinal tract, and histamine H2-blockers prolong the half-life and reduce total and renal clearance.

In case of an overdose of Abaktal, you should immediately seek medical help. Symptoms of overdose may include nausea, vomiting, diarrhea, abdominal pain, dizziness, seizures, and coma.

The dosage of Abactal depends on the type and severity of the infection, as well as the age and condition of the patient. The generally recommended dose for adults is 400 mg twice daily for 7 to 14 days. For some infections (eg, infective endocarditis), the dose may be increased to 800 mg twice daily. For patients with impaired renal or hepatic function, dosage adjustment may be required.

Overall, Abactal is an effective antimicrobial drug that can be used to treat a wide range of infections. However, as with any other medicine, you must carefully follow the instructions for use and follow your doctor's recommendations.