Acantholytic cells

Acantholytic cells (s. acantholyticae, synonym: tsanka cells) are epidermal cells that have lost adhesion to neighboring cells. They are characterized by a round or spindle-shaped shape, increased size and light cytoplasm.

Acantholytic cells are formed in some skin diseases accompanied by disruption of intercellular contacts in the epidermis. Such diseases include pemphigus, pemphigus vulgaris, Darier's disease, pemphigus vegetans, etc.

Microscopic examination reveals accumulations of acantholytic cells in the affected areas of the skin, which is a pathognomonic sign of this group of dermatoses. Thus, identifying acantholytic cells has important diagnostic value.



Acantholytic cells are specialized cells of the epidermis that perform the function of self-defense of the body. This type of cell forms on the skin in response to various irritants, such as ultraviolet light or infections.

Acanthollite cells are located on the surface of the skin and secrete many substances that can protect the skin from harmful bacteria and viruses. Also, these cells promote skin renewal and help maintain its health.

However, Acanmolytic cells are in a constant process of dividing and dying, which can lead to an excess of them on the skin. In this case, many skin lesions appear, including dryness and itching. Additionally, an excess of these cells can cause scaly skin to appear, which can make it feel rough and rough.

The appearance of Acantholytic cells on the skin can be associated with various reasons, such as impaired