Acriflavine

Acriflavine is a dye used in the preparation of antiseptic skin preparations, as well as for the disinfection of infected wounds. May cause increased skin sensitivity to sunlight.

AKRO- (aero-) - a prefix indicating:

1. Relation to limbs. For example: acrohypothermia (acrohypothcrmy) - painful coldness of the extremities (feet and hands).

2. Attitude to altitude. For example: acrophobia - a painful fear of heights.

3. Excessive manifestation of any symptom. For example: acromania (acromania) - an extreme degree of manifestation of mania.

Acriflavine is an organic compound, a derivative of acridine, used as a dye in analytical chemistry and for staining histological sections.

In 1932, G. Cassin and P. Mori carried out a synthesis and obtained a salt of acrylic acid with 8-aminoacridine-7-sulfonic acid, which was called “acroflav”. In 1940, M. Cooper and D. E. Gower established that "acroflav" is a crystalline powder that, when heated, forms a salt - acridine-2,7-disulfonic acids.

Acriflavine hydrochloride (acriflavine) is a medicine used to treat infected wounds and also as a skin antiseptic. It has weak antimicrobial activity, but may cause increased skin sensitivity to sunlight.

Acro- (English aero-) is an obsolete prefix, not currently used.

Acriflavin is a synthetic nitrogen-containing yellow dye belonging to the class of acridone dyes. It was opened in 1939. Soluble in water and alcohol. The compound is used as a developer for photographs. Acrylic color extract ranges from 56 to 70 colors. It is also used in medicine to create antiseptics, disinfect wounds and disinfect surfaces. Since this dye can cause a reaction in ultraviolet radiation sensitivity, its use in photographic developers is limited to a certain degree of dilution with distilled water (which greatly increases the rate of crystallization of the non-hydrated ferrous compound), at which reaction with organic substrates is completely eliminated

Unlike many diphenylamine dyes, it readily stains both quinine hydroquinone and hypoxanthine guanine phosphodiester. As a result, red-brown dyes are obtained - oxyalloxan and psophysal, which are used in photography. These two reactions and some others (for example, the oxidation of hydroxylamines) are obash reactions for acriflavine