Axamon

Aksamon: cholinesterase inhibitor from Russia

Axamon is a drug that belongs to the group of cholinesterase inhibitors. It is produced in Russia by the company Pik-Pharma and has the international name Ipidacrine. It is also known under the synonym Neuromidin. Aksamon is available in the form of tablets of 0.02 g, and its active substance is Ipidacrine.

Indications for use

Axamon is used to treat diseases of the peripheral nervous system in adults, such as neuritis, polyneuritis, polyneuropathy, polyradiculoneuropathy, myasthenia gravis. It can also be used for bulbar palsy and paresis, organic lesions of the central nervous system accompanied by nervous disorders (recovery period), demyelinating diseases (complex therapy) and intestinal atony.

Contraindications and side effects

Axamon should not be used in case of hypersensitivity to its components, epilepsy, extrapyramidal disorders, severe bradycardia, angina pectoris, bronchial asthma, vestibular disorders, gastric ulcer in the acute stage, pregnancy and breastfeeding.

Side effects that may occur when using Axamon include dizziness, bradycardia (can be eliminated with m-anticholinergics), hypersalivation (can be eliminated with m-anticholinergics), nausea, vomiting, itching and rash.

Interaction with other drugs

Aksamon enhances the sedative effect of drugs that depress the central nervous system. M-cholinomimetics and other cholinesterase inhibitors can enhance the effect and side effects of Axamon, increasing the risk of a cholinergic crisis, especially in patients with myasthenia gravis. Beta-blockers cause bradycardia if they were used before treatment with Axamon. When used simultaneously with alcohol, adverse side effects may increase.

Overdose and special instructions

In case of an overdose of Axamon, it is necessary to prescribe m-anticholinergics, including atropine, cyclodol and other analogues.

The drug increases the muscle tone of the uterus and can cause premature labor, so when using it, caution must be exercised in case of a stomach ulcer, as well as in the presence of other diseases that can be aggravated by increased muscle tone.

You should also be careful when using Axamon in elderly patients, as well as in patients with liver and kidney diseases.

Before starting treatment with Axamon, you must consult your doctor and strictly follow his recommendations on dosage and duration of treatment.

In general, Aksamon is an effective drug for the treatment of diseases of the peripheral nervous system, but its use should be carried out only after prescription by a doctor and under his supervision.