Amyridine

Country of origin - Russia, GNIISKLS Russia, Olainfarm Olaine Chemical Plant Latvia
Pharm-Group - Cholinesterase inhibitors

Manufacturers - unspecified company (Russia), GNIISKLS (Russia), Olainfarm Olainskiy HFZ (Latvia)
International name - Amiridin
Dosage forms - substance, tablets 20 mg
Composition - Active ingredient - ipidacrine.

Indications for use - Diseases of the nervous system: neuropathy, neuritis, polyneuritis, myelopolyradiculoneuritis, bulbar palsy and paresis due to organic lesions of the central nervous system, accompanied by motor disorders; myasthenia gravis and myasthenic syndrome; multiple sclerosis and other demyelinating diseases of the nervous system; functional disorders of the central nervous system (decreased memory, concentration, motivation, initiative, disorientation, emotional lability, etc.) with senile dementia, Alzheimer's disease, encephalopathy, cerebrovascular accident, traumatic brain injury, cerebral dysfunction with learning difficulties in children; intestinal atony, weakness of labor; intoxication with anticholinergic drugs.

Contraindications - Hypersensitivity, extrapyramidal disorders accompanied by hyperkinesis, epilepsy, bronchial asthma, angina pectoris, bradycardia, tendency to vestibular disorders, pregnancy, breastfeeding (breastfeeding should be stopped during treatment).

Side effects - Allergic reactions: skin itching, rash. Other: m-cholinomimetic effects - bronchospasm, bradycardia, hypersalvation, diarrhea; anorexia, nausea and vomiting, jaundice, dizziness, ataxia.

Interaction - Weakens the inhibitory effect on neuromuscular transmission and the conduction of excitation through the peripheral nervous system of local anesthetics, antibiotics, and potassium chloride. Atropine and methocinium iodide relieve symptoms of overdose and individual hypersensitivity.

Overdose - No information.

Special instructions - If side effects occur, the dose should be reduced (discontinuation of treatment is usually not required).

Literature - Encyclopedia of Medicines 2004.