Arsenic polyneuritis

Arsenic polyneuritis is an inflammation of the peripheral nerves caused by arsenic poisoning.

Causes

Arsenic polyneuritis usually occurs with long-term exposure to small doses of arsenic, which can be found in drinking water, food or air. Arsenic poisoning can occur when working in glass, ceramics, paint, and pesticide manufacturing plants.

Symptoms

The main symptoms of arsenic polyneuritis:

  1. numbness, tingling and pain in the extremities, most often in the feet and hands

  2. muscle weakness

  3. sensory disturbance

  4. muscle cramps

  5. loss of reflexes

Symptoms usually appear 2 to 8 weeks after exposure to arsenic begins and tend to progress over several months after exposure to the toxin ceases.

Diagnosis and treatment

The diagnosis of arsenic polyneuritis is made on the basis of the clinical picture and a blood test for arsenic content.

Treatment primarily involves stopping contact with arsenic and prescribing chelators (drugs that bind and remove the toxin from the body). Physical therapy and medications can help relieve pain and muscle weakness. Full recovery may take several months to a year.

The prognosis with timely treatment is usually favorable, but residual effects such as muscle weakness and sensory disturbances are possible. Preventive measures include compliance with industrial safety rules and monitoring the quality of drinking water.