Artifact (Artifact, Artefact) is a term used in microscopy to describe a structure observed in tissue under the microscope, but not existing in living tissue. Artifacts can occur for various reasons, such as insufficient tissue fixation, incorrect placement under the microscope, and preparation errors.
Artifacts may give the false impression of the presence of a disease or abnormality when in fact it is not present. This can lead to misdiagnosis and unnecessary treatment. Therefore, it is important to consider the possibility of artifacts and be able to recognize them.
One of the most common artifacts is the motion artifact. It occurs when a sample is not sufficiently fixed and begins to move when observed under a microscope. This may result in blurred images and distorted shapes of objects. Another common artifact is distortion artifact, which occurs when the sample is placed incorrectly under the microscope or when incompatible components are used in the slide.
To avoid artifacts, it is necessary to properly prepare the sample before observing it under a microscope. This includes properly fixing the tissue, cutting it, and placing it on the slide. In addition, it is necessary to correctly set up the microscope and use the appropriate components in the preparation.
In conclusion, artifacts are an important aspect of microscopy and can have a significant impact on study results. Understanding the possible causes of their occurrence and the ability to recognize them will help to avoid diagnostic errors and obtain more accurate research results.
Artifact in microscopy
An artifact is a structure that is observed in tissue under a microscope and is not present in living tissue. In microscopy, artifacts can arise from insufficient fixation and improper placement of tissue under the microscope. This can lead to a false perception of the presence of some disease or tissue abnormality when in fact there is none.
There are several types of artifacts in microscopy. One of them is optical artifact, which occurs due to the reflection of light from the surface of the tissue. Another type is diffraction artifact, which occurs due to the diffraction of light at tissue boundaries.
To avoid artifacts during microscopy, it is necessary to properly fix and position the tissue under the microscope. Special specimen preparation techniques such as formalin fixation or paraffin embedding may also be used.
In general, artifacts in microscopy can lead to misdiagnosis and false conclusions. Therefore, it is important to know and consider the different types of artifacts to avoid their negative impact on the results of microscopic examination.
In microscopy, an artifact is a structure that is observed in tissues under microscopic observation, whereas in living tissues it is absent - “Artifact”.
Artifacts are the reason for the emergence of false conclusions about the presence of any disease of the body or its anomalies, when in fact nothing was found. Most often, artifacts arise from incorrectly positioned or poorly mounted tissue samples on the microscope, thereby disturbing the natural environment of the tissue samples.
In modern life, artifacts can be attributed to errors in the assembly or manufacturing stages. If we talk about artifacts associated with medical research, this may be due to improper fixation of a tissue sample in a special solution. Such methods can lead to false results in the diagnosis of diseases, although in fact the patient may not be sick.
In addition, artifacts can result from improper sample detection techniques and methods during laboratory testing. Here are some of them that can provoke the appearance of artifacts: - incorrect sampling; - incorrect blood sample; - malfunction of laboratory instruments; - inconsistency of the methods being studied.
Many management systems for medical institutions have a variety of protective mechanisms that minimize the consequences of possible artifacts. At particularly critical stages and during complex and lengthy research, virtual production, robotic technology and automation are used. Also, to improve the accuracy and reliability of research, new methods are used (remote diagnostics, artificial intelligence, genetics, computer technology, etc.).