A irritation artifact (DR), in electrophysiology, is a phenomenon in which recorded signals deviate from expected values due to the presence of pulsed stimuli applied to a tissue or body surface. This deviation may be associated not only with a change in the electrical properties of the tissue, but also with a direct mechanical effect on the recording device. Strong DR can lead to false positives or false negatives, which can affect the interpretation of experimental data. To minimize DR, artifact suppression and filtering methods are used, which allow you to get rid of unwanted influences while maintaining significant fluctuations in electrograms. However, it is important to consider the characteristics of each specific experiment, since different applications of additional methods may require non-standard solutions to eliminate DR.
Artifact of Irritation in Electrophysiology
An irritation artifact is a phenomenon in electrophysiological studies in which, when recording the activity of biological tissues, a deviation in the recorded curve may occur, which is due to the external influence of the irritant (for example, electrical or chemical) on the surrounding tissue or equipment. As a result, the curve may be distorted, making it difficult to analyze the data obtained.
Such deviations arise due to the physical impact of irritants, as well as due to the characteristics of the device
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