The main peroneal artery (common costal) (arteria peronae communis, a. peronea communis, synonym - a. pericranialis communis) is a continuation of the posterior tibial artery and occupies the same name with its branch in this place. It passes through the tibial notch and ends in the common fibular pad of the inner part of the leg. This artery is one of the important vessels for providing blood supply to the muscles of the leg and foot. An important circumstance is also the fact that the most important blood supply routes to the brain and heart are connected to the lumen of the artery. Further in the article, her anatomical study is presented using relevant knowledge from the field of topographic anatomy. **The length of the arta is determined by the distance from the base of the skull to the lower border of the pubic angle.** The small size of the vessel is compensated by a dense network of anastomoses that form numerous mutual connections of segmental trunks, so blood circulation is distributed fairly evenly to the limbs. The blood supply to the arteries of the head and neck comes from the brachiocephalic trunk. In addition, this is facilitated by the arterial network located in the area of the aortic arch and subclavian region. This network is replenished by tributaries from the vertebral arteries. The arteries of the mandible, tongue, larynx and face receive blood from the cervical brain trunk, as well as from the vertebral arteries and aa. located in the external parts of the bases of the occipital bone, the pyramids of the temporal bones.