Aspirin: Anti-inflammatory drug and its characteristics
Aspirin, or acetylsalicylic acid, is one of the most famous and widely used drugs in the world. It belongs to the group of anti-inflammatory drugs derived from salicylic acid. Aspirin is widely used to relieve pain, reduce inflammation and fever, and to prevent thrombosis and thromboembolism. In this article, we will look at various aspects of this drug, including its manufacturers, dosage forms, composition, indications for use, contraindications, side effects and interactions with other drugs.
Manufacturers of aspirin on the world market include companies such as Bayer AG (Turkey and Germany), Bryntsalov (Russia), Yangsu Yangshan Pharmaceutical Co Ltd (China), Cox (Great Britain), Concern Stirol (Ukraine), L.T. York Company and LNK International Inc. (United States of America), M and A Pharmachem Ltd. Vel and others.
Aspirin is available in a variety of dosage forms, including tablets of various strengths (from 75 mg to 500 mg), effervescent tablets, dispersible tablets and soluble tablets. The active substance is acetylsalicylic acid.
Indications for the use of aspirin include the treatment of rheumatism, rheumatoid arthritis, infectious-allergic myocarditis, fever due to infectious-inflammatory diseases and pain syndrome of various etiologies, such as headache, migraine, toothache, neuralgia, myalgia, arthralgia, algomenorrhea. Aspirin is also used to prevent thrombosis and thromboembolism, including myocardial infarction, coronary heart disease, unstable angina, cardiac arrhythmias and other cardiovascular diseases.
However, aspirin has some contraindications. It is not recommended for hypersensitivity to the drug, erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, gastrointestinal bleeding, aspirin-induced asthma, bleeding disorders, severe renal failure, in the first trimester of pregnancy and during lactation. Caution should also be exercised when prescribing aspirin to children and the elderly with concomitant diseases.
Side effects may occur when using aspirin. Some of them include gastrointestinal irritation, dyspeptic symptoms, gastroduodenal ulcers, allergic reactions, bleeding, increased risk of ketoacidosis in patients with diabetes, impaired renal function and others.
It is also important to consider the possible interactions of aspirin with other drugs. For example, aspirin can enhance the effects of anticoagulants, glucocorticosteroids and alcohol, and also interact with some antihypertensive and antidepressant medications.
Before starting to use aspirin, you should consult your doctor or pharmacist to evaluate indications and contraindications, as well as possible side effects and interactions with other drugs.
It is important to remember that this information does not replace consultation with a specialist and is not a guide to self-medication.