Azotemia Extrarenal

Azotemia is a condition in which the concentration of nitrogen in the blood increases, which can be caused by various reasons. One of the forms of azotemia is Extrarenal Azotemia, which occurs when kidney function is impaired and is not associated with diseases of the kidneys themselves.

Extrarenal azotemia can be caused by various reasons, such as:

  1. Liver diseases that lead to impaired kidney function.
  2. Infectious kidney diseases such as pyelonephritis or glomerulonephritis.
  3. Kidney toxicity, such as from certain medications or chemicals.
  4. Diabetes mellitus, which can damage the kidneys and impair their function.
  5. Obesity, which can increase the risk of developing kidney disease.
  6. Circulatory failure, which can lead to decreased blood supply to the kidneys.
  7. Hereditary kidney diseases, such as polycystic disease or hereditary nephritis.
  8. Metabolic disorders such as gout or hyperuricemia.
  9. Urinary tract diseases such as urolithiasis or urethritis.
  10. Kidney injuries, which can lead to impaired kidney function and the development of azotemia.

Azotemia Extrarenal can present with a variety of symptoms, including:

– Increased levels of nitrogen in the blood, which can lead to fatigue, weakness and decreased appetite.
– Swelling, especially on the face and legs.
– High blood pressure.
– Headaches and dizziness.
– Gastrointestinal disturbances, including nausea, vomiting and diarrhea.
– Change in the color of urine, which may be darker or have a foul odor.
– Decreased diuresis (the amount of urine excreted per day).

To diagnose extrarenal azotemia, it is necessary to conduct a blood test to measure nitrogen levels and other indicators of kidney function.



Azotemia is a violation of the excretory function of the kidneys. As a result of this disorder, nitrogenous compounds are not excreted from the body along with the urine, and residual blood nitrogen, urea, creatinine, uric acid, nylon, indole, and ammonia appear and increase in quantity.

Manifestations of azotemia are associated with:

development of renal failure (arrhemia),

cerebrovascular insufficiency (arrhythmia).

kidney nutritional disorders (amiconia),

pyelonephritis, glomerulonephritis, etc.

Azotemia is diagnosed in pregnant women and residents of areas with unfavorable ecology, after poisoning with industrial poisons, and in people with kidney pathology. A change in urinary excretion leads to a decrease in the glomerular filtration rate, the disappearance of primary filtration of blood in the kidney, and its destruction. Aotemia is most dangerous for children and young people, because It takes time for the nephrons to restore their nitrogen excretion function.