Ballentyne-Runge Syndrome

Ballentine-Rung syndrome

Ballentine-Range syndrome is a rare disease that usually appears during pregnancy and is characterized by extremely high levels of prolactin in the blood. This condition is characterized by developmental disorders in the fetus and the fetus in the mother. This syndrome was first described in 1957 by James Vajas Baldent and Nikolaus Runge.

The main factors contributing to the development of this syndrome are chronic stress and overexertion of the pregnant woman's body, urinary tract infections in the mother and certain medications taken by the pregnant woman during pregnancy. Chronic stress can lead to increased prolactin levels,

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**Introduction**

Ballintai-Runne syndrome

Ballantyne–Runge syndrome is a rare autoimmune disease in which cells of the immune system mistakenly attack healthy tissues and organs. The most common target organs are the liver, thyroid, brain, ovaries and uterus. Although this disease is quite rare (with an estimated annual incidence of 220 cases worldwide), it causes a wide range of clinical manifestations and can lead to serious health consequences. Timely diagnosis and appropriate treatment will help prevent dangerous complications and increase the chances of a full recovery. In 1986, A.D. Balkantain outlined the pathogenesis of the syndrome: a lack of cortisol in the blood leads to increased synthesis in the adrenal cortex, which increases the likelihood of developing various autoimmune disorders (for example, Addison's disease). As a result, many experts suggest that the occurrence of this disease is associated with hypopituitarism. A similar position is taken by a member of the Moscow International Society of Endocrinologists, Professor Vladimir Prokhorov. N. Runge, from