Berezovsky-Sternberg Cells

Berezovsky-Stern cells (syn. Reed-Berezovsky-Sterenberg cells) are a type of malignant cell that was first described by the German pathologist Carl Sterenberg in 1890. These cells are oval or round in shape and contain one or more nuclei located in the center. They can be dyed in different colors, depending on the dye used.

Berezovsky-Sternberg cells are a form of lymphoid cells and are malignant cells that form in the lymph nodes and other tissues of the body. They can cause a variety of diseases, including lymphadenopathy, lymphoma and other types of cancer.

Research suggests that these cells may be associated with a variety of factors, including viral infections, genetic mutations and chemical exposure. Treatment for Berezovsky-Sternberg cells may include chemotherapy, radiation therapy, and surgical removal of the affected tissue.

Berezovsky–Sternberg cell is a cell formed during a chronic inflammatory process in the lymph nodes of patients with HIV infection and AIDS, since the patient’s lymphocytes are able to retain the ability to transform into T-killer cells of a malignant neoplasm. The disease associated with the formation of these cells is called Castleman's disease (endematous large cell lymphoma).