Prussian blue

Prussian blue is a water-insoluble complex ferric-cyanide salt of trivalent iron, which has a dark blue color. It is widely used as a dye in histological techniques.

The Prussian blue formation reaction is used for the histochemical detection of ferric iron salts in cells and tissues. When interacting with Fe3+ salts, Prussian blue forms an insoluble precipitate of intense blue color. This allows iron to be detected and localized in histological sections to study its distribution and role in the body.

Thanks to its bright blue color, Prussian blue contrasts well with the background of tissues and gives a clear idea of ​​the localization of iron in cells. This reaction is widely used in histochemistry to detect iron deposits in various pathologies, as well as to study the normal distribution of Fe3+ ions in organs and tissues.



***Prussian blue***

**Synonyms:** Iron (III) dihydrogen carbonate x dihydroxide oxidano-biguanidate tetrahydrate (III), iron III, redox salt.

The iron-containing substance *Fe2(OH)3* (II) (light yellow precipitate, *dark yellow when heated*) has a high *pH value*. When heated, it decomposes into **Prussian blue *(Fe4[Fe(CN)6]3.2H2O)* **and **Coal blue** - a dark blue powder with low solubility in an aqueous environment.

*Fe3(OH)2* – **poorly soluble in water red-brown oxide with a violet tint and a pungent odor**.

At ordinary temperatures, it looks like an inorganic compound firmly connected to oxygen (not an acid, rather a base). Used as a **dye in histology**, analytical chemistry and flotation of copper-cobalt ores. It dissolves with great difficulty with chlorides, especially sulfuric acid, and loses its shine.



Name: Berlin Lazur ***Description***

Berlinlazurite (oxidized iron - hematite) is a water-insoluble complex ferrous salt of the synergous salt of ferrous iron, having a dark blue color.

It is used in histology during diagnostic tests using the hematoloff method. When amylazine, a blue or blue buffer solution, is added, this alkaline liquid forms a bright blue complex. This complex allows you to view water droplets deep in the wall. Other dyes such as iodine or metamalac are also used for syneresis. Due to its inherent coloring properties, this chemical is used in the differential diagnosis of many types and forms of cancer, as well as other diseases.

While excess consumption of Berlin lapis lazuli through oxidative cellular reactions dilutes the protective barriers of the autoimmune system, low stainings likely contribute to the development of autoimmune diseases. Depending on the specific disease that develops from excessive consumption of Prussian lapis lazuli, symptoms may include fatigue, exhaustion, joint pain, bruising, muscle weakness