Betacard-100

Country of origin: India
Pharm-Group: Beta1-blockers (cardioselective)

Manufacturers: Torrent Pharmaceuticals (India)
International name: Atenolol
Synonyms: Azectol, Apo-Atenol, Aten, Atenil, Atenobene, Atenova, Atenol, Atenolan, Atenolol, Atenolol Nycomed, Atenolol FPO, Atenolol-AKOS, Atenolol-Akri, Atenolol-Ratiopharm, Atenolol-Ratiopharm 100, Atenolol-Ratiopharm 25, Atenolol-Ratiopharm 50, Atenolol-Teva, Ateno

Dosage forms: film-coated tablets 100 mg
Composition: Active substance - Atenolol.

Indications for use: Arterial hypertension, angina pectoris, acute myocardial infarction (with stable hemodynamic parameters), tachycardia: sinus, atrial, ventricular, paroxysmal, etc., extrasystole, atrial flutter and fibrillation, hyperkinetic cardiac syndrome, mitral valve prolapse, neurocirculatory dystonia according to hypertensive type; complex therapy of hypertrophic cardiomyopathy, pheochromocytoma, thyrotoxicosis, essential tremor; migraine (prevention).

Contraindications: Hypersensitivity, sinus bradycardia (heart rate less than 50 beats/min), sinoatrial block, sick sinus syndrome, AV block II-III degree, arterial hypotension (systolic blood pressure less than 90 mmHg), acute or chronic heart failure in the stage of decompensation, cardiogenic shock, peripheral circulatory disorders, breastfeeding.

Side effect:

1. From the nervous system and sensory organs: increased fatigue, weakness, dizziness, headache, drowsiness or insomnia, nightmares, depression, anxiety, confusion or short-term memory loss, hallucinations, decreased reactivity, paresthesia, convulsions; blurred vision, decreased secretion of saliva and tear fluid, conjunctivitis.

2. From the cardiovascular system and blood: bradycardia, palpitations, myocardial conduction disturbances, AV block, arrhythmias, weakened myocardial contractility, heart failure, hypotension, syncope, Raynaud's phenomenon, vasculitis, chest pain, thrombocytopenia, agranulocytosis.

3. From the gastrointestinal tract: dry mouth, nausea, vomiting, abdominal pain, diarrhea, constipation, liver dysfunction.

4. From the respiratory system: shortness of breath, laryngo- and bronchospasm.

5. Allergic reactions: itching, rash, erythema, urticaria, psoriasis-like and dystrophic skin changes.

6. Other: reversible alopecia, hyperhidrosis, cold extremities, myasthenia gravis, decreased libido, impotence, Peyronie's disease, changes in enzyme activity, bilirubin levels, withdrawal syndrome, hypothyroid state, hypoglycemia.

Interaction:

Antiarrhythmic and anesthetic drugs enhance the cardiodepressive effect. Reserpine, alpha-methyldopa, clonidine, guanfacine, cardiac glycosides potentiate the negative chrono-, dromo- and bathmotropic effect, insulin and other antidiabetic drugs - hypoglycemia.

NSAIDs, estrogens, sympathomimetics, xanthines weaken the hypotensive effect, sympatholytics, nitroglycerin, apressin and other antihypertensive drugs, antacids enhance. Cimetidine inhibits metabolism.

Tri/tetracyclic antidepressants, antipsychotics, sedatives, hypnotics and alcohol potentiate CNS depression. Incompatible with MAO inhibitors.

Overdose:

Symptoms: bradycardia, AV block II-III degree, heart failure, respiratory failure, hypotension, bronchospasm, hypoglycemia.

Treatment: gastric lavage, adsorbents, atropine, isoprenaline, orciprenaline.

Special management