Defibrinized blood is blood from which fibrin has been removed. Fibrin is a protein that is the main component of blood clots that form during blood clotting. Therefore, defibrinated blood is not able to clot and turn into blood clots.
The defibrinization process can be achieved in various ways. For example, the blood may be treated with enzymes such as thrombin or plasmin, which break down fibrin. Defibrinization can also be achieved by treating the blood with solutions of ethylene glycol or heparin.
Defibrated blood is widely used in medicine. For example, it can be used as a plasma substitute for injuries and blood loss, since it does not form blood clots and does not interfere with blood circulation. It can also be used to perform laboratory tests such as a coagulation test, which evaluates blood clotting.
However, it should be noted that defibrinated blood does not contain fibrinogen, which is the main precursor of fibrin. Therefore, when using it as a plasma substitute, it is necessary to take this fact into account and additionally administer fibrinogen.
Thus, defibrinated blood is an important component of medical practice that can be used in various situations. However, it is necessary to take into account its features and apply it taking into account the specific needs of the patient.