Bupremen

Country of origin: India
Pharm-Group: Narcotic analgesics of the morphine group and their analogues

Manufacturers: Menon Pharma (India)
International name: Buprenorphine
Synonyms: Anfin, Bupranal, Buprenorphine hydrochloride, Bupresic, Nopan, Norfin, Sangesic, Torgesic, Transtek, Ednok
Dosage forms: tablets 0.2 mg, solution for injection
Composition: Active substance - buprenorphine.
Indications for use: High intensity pain syndrome (after surgery, in cancer patients, myocardial infarction, renal colic, burns).
Contraindications: Hypersensitivity, physical dependence; conditions accompanied by respiratory depression or severe depression of the central nervous system; convulsive conditions; increased intracranial pressure; traumatic brain injury; acute alcoholic states and alcoholic psychosis; bronchial asthma; paralytic ileus; cardiopulmonary failure, heart rhythm disturbances; pregnancy and lactation; children up to 16 years of age.
Side effects: Headache, dizziness, sweating, dry mouth, nausea, vomiting, hypotension, lethargy, depression of the respiratory center, slower speed of respiratory and motor reactions, skin rash.
Interaction: Strengthens (mutually) the main and side effects, as well as the toxicity of MAO inhibitors and central nervous system depressants (tranquilizers, antipsychotics).
Overdose: In case of overdose, a stuporous or comatose state, hypothermia, hypotension develops, respiratory depression, and constriction of the pupils are observed. Treatment: Naloxone is administered, as well as symptomatic medications.
Special instructions: It is not recommended to use during and after short surgical interventions. Should not be used during treatment with MAO inhibitors and for another 14 days after their discontinuation. Use with caution in elderly patients, with general exhaustion, liver and kidney diseases, and insufficiency of the adrenal cortex. During treatment, it is not recommended to engage in activities that require concentration and speed of psychomotor reactions.
Literature: Encyclopedia of Medicines, 2005.