Country of origin: Türkiye
Pharm-Group: Alpha-adrenergic receptor stimulating agents
Manufacturers: Kurtsan Ilachlari (Türkiye)
International name: Tetrizoline
Synonyms: Vizin, Octilia, Tizin
Dosage forms: nasal solution 0.05%, nasal solution 0.1%
Composition: Active ingredient - tetrizoline.
Indications for use: Irritation, itching and redness of the eye, allergic conjunctivitis, swelling of the mucous membrane of the nasal cavity and nasopharynx.
Contraindications: Hypersensitivity. Restrictions on use: Eye drops: severe eye diseases (angle-closure glaucoma, etc.), children (up to 3 years). Nasal drops: children's age (up to 2 years).
Side effects: Eye drops - mydriasis, increased intraocular pressure, burning sensation and reactive hyperemia of the eye. Rarely - increased blood pressure, tachycardia, nausea, headache, hyperglycemia, allergic reactions. Nasal drops - burning and tingling in the nose, sneezing, dry nasal cavity, headache, drowsiness, weakness, tremor, dizziness, sleep disturbance, palpitations. With prolonged use or exceeding the dose, secondary swelling of the nasal mucosa occurs.
Interaction: Incompatible with MAO inhibitors.
Overdose: Manifested by systemic arterial hypertension.
Special instructions: Use with caution in patients with arterial hypertension, hyperthyroidism, heart disease, diabetes mellitus, during pregnancy and lactation. With prolonged use or accidental ingestion, toxic effects may develop. The dosage regimen must be strictly observed. If within 48 hours after starting the use of eye drops no effect is observed or a side effect occurs, the drug should be discontinued.
Literature: Encyclopedia of Medicines 2004