Chlorpromazine (Chlorpromavne)

Chlorpromazine (Chlorpromavne) is an antipsychotic drug from the group of phenothiazines; used to treat schizophrenia and manic psychoses. In addition, it can be used to treat severe anxiety and agitation, and as an antinausea and antiemetic. It enhances the effect of analgesics, therefore it is often used in hopelessly ill patients in a state of agony and in preparation for anesthesia. Chlorpromazine can be given orally, by injection, or as a rectal suppository; Typical side effects are drowsiness and dry mouth. Various movement disorders, especially dystonia, dyskinesia and parkinsonism, may also be observed. Trade name: Largactil.

Chlorpromazine

Chlorpromazine (Chlorpromavne) is an antipsychotic drug from the group of phenothiazines; used to treat schizophrenia and manic psychoses. In addition, it can be used to treat severe anxiety and agitation, and as an antinausea and antiemetic. It enhances the effect of analgesics, therefore it is often used in hopelessly ill patients in a state of agony and in preparation for anesthesia. Chlorpromazine can be given orally, by injection, or as a rectal suppository; Typical side effects are drowsiness and dry mouth. Various movement disorders, especially dystonia, dyskinesia and parkinsonism, may also be observed. Trade name: Largactil.

Chlorpromazine is a phenothiazine derivative, an antipsychotic of moderate strength; a specific tricyclic antidepressant with alpha1-adrenergic blocking activity. In terms of analgesic properties it is 2 times inferior to reserpine; in terms of anxiolytic action, chlorpromazine is inferior to ethanol, cyclobarbital and diazepam. Unlike reserpine, it causes a moderate stimulating effect on the central nervous system.

The drug has a complex antipsychotic, sedative, anxiolytic, antihistamine, hypothermic and adrenolytic effect. It has an antihypoxic effect, increases the body's resistance to various chemical influences. The antipsychotic effect is due to blockade of D2 receptors, catalytic disturbances in catecholamine metabolism, and blockade of H1 receptors. Sedative effects are associated with depression of the central nervous system, analgesic and emetic effects are associated with blockade

CHLORPROMAZINE

Chlorpromazine is a synthetic drug that belongs to the group of typical neuroleptics-phenothiazines, that is, antipsychotic drugs that have a depressant effect on the nervous system. It is popular among patients mainly due to its