Dobutamine (Dobutamine)

Dobutamine is a sympathomimstic drug that helps reduce heart failure. Increases ventricular contractility and increases cardiac blood output; can be prescribed for long-term treatment (used intravenously).

Dobutamine stimulates the β1-adrenergic receptors of the myocardium, which leads to an increase in the strength and frequency of heart contractions. This allows you to increase cardiac output and reduce end-diastolic pressure in the left ventricle.

The drug is used for acute and chronic heart failure, cardiogenic shock, and decreased cardiac output after cardiac surgery.

Dobutamine is administered intravenously by drip, the initial dose is 2-5 mcg/kg/min with a gradual increase to 10-20 mcg/kg/min. The action develops quickly and lasts 5-10 minutes after stopping the infusion.

Side effects include tachycardia, ventricular arrhythmias, headache, tremor. The drug is contraindicated in hyperthyroidism, pheochromocytoma, and aortic valve stenosis. Dobutamine should be used with caution in elderly patients and those with coronary artery disease.



Dobutamine is a sympathomimetic drug that is widely used in cardiology to reduce the manifestations of heart failure. This drug increases the contractility of the ventricles of the heart, increases cardiac blood output and reduces the load on the heart muscle.

Dobutamine is a selective adrenergic agonist that stimulates beta-1 adrenergic receptors of the heart, which leads to increased myocardial contractility and increased cardiac output. At the same time, dobutamine does not have a significant effect on peripheral resistance, which allows its use in the treatment of heart failure with preserved left ventricular systolic function.

Dobutamine can be used as both short-term and long-term therapy. It is usually used intravenously by drip with a gradual increase in dose until the desired effect is achieved. At the same time, the dosage and rate of administration depend on the severity of the patient’s condition and the required level of cardiac stimulation.

Additionally, dobutamine can be used as a diagnostic tool to assess cardiac systolic function. In this case, the drug is administered intravenously in small doses, and then an echocardiographic study is performed to evaluate changes in blood volume in the ventricles of the heart.

Although dobutamine is considered a relatively safe drug, it has a number of side effects that can manifest itself in the form of headaches, nausea, increased blood pressure, arrhythmias and other manifestations. Therefore, before prescribing it, it is necessary to carefully assess the patient’s condition and select the optimal dose and mode of administration.

Overall, dobutamine is an important drug in cardiac practice that can improve cardiac function and quality of life in patients with heart failure. However, its use should be limited and only under medical supervision.



**Dobutamine** (dopmina) is a sympathomimetic drug that is often used to treat heart disease and heart failure (reduced blood flow or circulation). It is also called an inotropic drug. Dobutamine improves cardiac function and increases cardiac