Clearance Test

Clearance is the process of cleansing the blood of toxins and breakdown products that are formed as a result of metabolism. It is an important indicator of the health and function of the kidneys, liver, and other organs and systems of the body. Clearance can be measured using special functional tests - clearance tests.

Clearance test is the general name of functional tests aimed at determining the clearance of any substances. These tests are used to study the function of the kidneys, liver and other organs in the study of metabolism, the biological cycle of hormones and to assess the effectiveness of hemodialysis.

One of the most common clearance tests is the Rehberg test. It assesses kidney function by measuring the volume of blood that passes through the kidneys per unit time and determines creatinine clearance. Creatinine is a product of protein metabolism and is excreted in the urine.

Another common clearance test is the Westergren test, which evaluates liver function by measuring the amount of bilirubin in the blood. Bilirubin is formed as a result of the breakdown of hemoglobin and is excreted in bile.

Rehberg and Westergren tests are simple and accessible methods for determining the clearances of creatinine and bilirubin, respectively. They are widely used in clinical practice for the diagnosis and monitoring of various kidney and liver diseases.

In addition, there are other methods for determining the clearance of various substances, such as the Hoffman test, a test using radioactive tracers, etc. Each of these methods has its own advantages and limitations, and the choice of method depends on the specific clinical situation and the goals of the study.

In general, clearance tests are an important tool for assessing renal and other organ function. They make it possible to determine the clearance of various substances and can be used for the diagnosis and control of various diseases. However, before performing a clearance test, you must consult your doctor and follow his recommendations.

Clearance test or clearance test is a method for studying the general functional activity of the kidney and some other metabolic systems. It is used in cases where it is necessary to determine the rate of elimination of a substance from the body. The functional state of this system is assessed by the amount of filtered substance per unit of time. The term “clearance” comes from the English “clearance” - purification.

When carrying out clearance tests, various drugs are used, which are administered intravenously along with radioactive tracers, which make it possible to measure as accurately as possible the removal of these drugs from the body per unit of time - clearance. The difference between this method is that it allows you to evaluate not only the process of removing drugs from the body, but also their metabolism, bioavailability and route of elimination (excretion).

Clearance tests are used in medicine to diagnose various diseases of the renal system, as well as to monitor the dynamics of existing pathologies (for example, chronic renal failure). This analysis also helps to identify the causes of disturbances in blood flow and electrolyte levels in the body. The clearance test should be performed in the morning, before meals and medications. This way the procedure will be the most informative and accurate. However, you should consult your doctor before taking the test. Sometimes the procedure can be dangerous or contraindicated. In addition, one should not forget about possible side effects after the testing procedure is completed. It is important to note that there are several types of clearance tests, each of which is used to determine a specific function of the body or organs. The most common are creatinine clearance, clearance of water-soluble compounds, total clearance of xenobiotics, and others.