Creatinuria

Creatinuria is an excess of the nitrogenous compound creatine in the urine.

Creatine is formed in the liver, kidneys and pancreas from the amino acids glycine, arginine and methionine. It plays an important role in energy metabolism in muscles. Normally, a small amount of creatine is excreted in the urine.

With creatinuria, there is an increased excretion of creatine in the urine. This may be due to hereditary diseases, kidney damage, and metabolic disorders.

Diagnosis of creatinuria is based on determining elevated creatine levels in 24-hour urine.

Treatment is aimed at correcting the underlying disease that caused the disturbance in creatine metabolism. Taking creatine as a dietary supplement may also lead to creatinuria.



Creatinuria is an excess amount of the nitrogenous substance creatine in the urine. Creatine is a breakdown product of creatine, which is an important source of energy for muscles and the nervous system.

Creatinuria can be caused by various reasons, such as:

  1. Lack of water in the body. With a lack of water, creatine cannot be completely eliminated from the body through the kidneys, which leads to its accumulation in the urine.
  2. Renal dysfunction. The kidneys play an important role in removing creatine from the body, so impaired kidney function can lead to creatinuria.
  3. Some medications. Some medications, such as antibiotics, can cause creatine levels in the blood to increase, which can cause it to be excreted through the kidneys.
  4. Excessive consumption of products containing creatine. If a person consumes too many foods that contain creatine, such as sports nutrition or meat, this can cause creatine levels in the body to increase and be eliminated through the kidneys.
  5. Some diseases. Some diseases, such as diabetes, can lead to impaired kidney function and increased levels of creatine in the body.

If creatinuria is detected in a patient, then additional studies must be performed to identify the cause of this condition. Depending on the cause, treatment may include lifestyle changes, medications, or surgery.

In general, creatinuria is a sign of impaired kidney function or other diseases, so it is necessary to see a doctor for diagnosis and treatment.



Creatinuria is an excessive concentration in the urine of the substance creatine, which is formed in human muscles to maintain their performance. Creatinuria is diagnosed when the amount of creatine in the urine exceeds the expected level, which depends on the patient's body weight and daily requirement in his body. The presence of creatinine in urine indicates that creatine from muscle cells cannot be completely converted into creatinine by the liver and is excreted in the urine. Typically, the kidneys filter water, salts, and creatine components from the bloodstream and remove them to the bladder. However, with an increased level of creatine concentration, the excretory channels of the kidneys become clogged. The appearance of creatinuria is associated with water deficiency in the human body or disruption of the functioning of a number of human organs or systems. In some cases, creatinuria is seen as an additional symptom of an electrolyte imbalance, such as potassium, magnesium, sodium, or calcium deficiency. It is necessary to monitor the condition of muscle and