Cyclophosphamide

Cyclophosphamide is a drug used to treat certain types of malignancies, often in combination with other cytotoxic drugs. Cyclophosphamide suppresses the functions of the immune system, therefore it is used to improve the engraftment of a tissue transplant, as well as in cases where it is necessary to reduce the immune response to changes occurring in the body.

Cyclophosphamide is given orally or by injection; possible side effects: nausea, vomiting and - especially when used in large doses - hair loss.

Trade name: Endoxana.

Cyclophosphamide is a drug used in the treatment of certain types of malignant tumors. Also used as an immunosuppressant.

Cyclophosphamide is a phosphoramide derivative. It inhibits DNA synthesis, suppressing mitosis and causing apoptosis. Cyclophosphamide also inhibits the synthesis of nucleic acids in tumor cells, which can lead to the death of these cells.

The drug can be used both as monotherapy and in combination with other drugs. For example, cyclophosphamide can be used in combination with doxorubicin (Adriamycin) or idarubicin (Idarubicin) to treat breast cancer.

As an immunosuppressant, cyclophosphamide is used to reduce the body's immune response to organ or tissue transplantation. It can also be used to reduce the reaction to various medical treatments such as radiation or chemotherapy.

Side effects of cyclophosphamide may include nausea, vomiting, hair loss, headache, anemia, thrombocytopenia, and other blood disorders.

The trade name for cyclophosphamide is Endoxan. It is available in the form of tablets and injection solutions.

Cyclophosphamide (cyclophosphamide): a medicinal compound from the group of alkylating drugs used in chemotherapy against tumors. Due to side effects such as bone marrow suppression and liver toxicity, cyclophosphamide has been replaced by azathioprine, immunosuppressants, glucocorticoids and other drugs [2]. Although it is not used in the treatment of leukemia and lymphomas, Cyclophosphamide may improve results in combination therapy to combat steroid-dependent types of lymphomas and multiple sclerosis. For multiple myeloma, the drug is used, but usually with the additional use of glucocorticoids. Prev