Country of origin: Mexico
Pharm-Group: Folic acid group
Manufacturers: Lemery (Mexico)
International name: Calcium folinate
Synonyms: Calciumfolinate-Ebewe, Calcium folinate, Leucovorin Ca Lahema 10, Leucovorin Ca Lahema 25, Leucovorin calcium, Leucovorin-Lance, Leucovorin-Teva, Sanphycinate, Calcium folinate
Dosage forms: solution for injection 12.5 mg/ml, solution for injection 3 mg/ml
Composition: Active substance - calcium folinate.
Indications for use: Methotrexate intoxication (treatment and prevention), megaloblastic anemia of iatrogenic origin, folinium hypo- and vitamin deficiency.
Contraindications: Hypersensitivity, pernicious and other megaloblastic anemia due to vitamin B12 deficiency. During pregnancy and breastfeeding, use only if absolutely necessary.
Side effect: Allergic reactions.
Interaction: Weakens the effect of methotrexate (including therapeutic.)
Overdose: No information.
Special instructions: Calcium folinate solution for infusion should be prepared ex tempore; It can only be used for 12 hours.
Literature: Encyclopedia of Medicines 2004.