Defibrinization

Defibrination is the process of removing fibrin from the blood, one of the proteins in the blood plasma that causes it to clot. Fibrin is a key component of blood clots, which form to stop bleeding when blood vessels are damaged. However, in some cases, such clots can form incorrectly and cause serious illnesses such as thrombosis and embolism. Defibrinization may be necessary to correct these problems.

Defibrinization is carried out using several thin wires onto which fibrin threads are wound and adhered to them. These wires are called defibrinizing wires. They are used to remove fibrin from the blood and prevent the formation of blood clots.

Defibrinization may be necessary in a variety of medical situations. It can be used to treat thrombotic conditions such as thrombosis and embolism, as well as to prevent their occurrence. Defibrinization may also be useful in cases where it is necessary to reduce blood clotting before surgery.

However, it should be noted that defibrinization may cause unwanted side effects such as bleeding. Therefore, the use of defibrinization should only be carried out under the supervision of qualified specialists.

In conclusion, defibrinization is an important treatment and prevention of thrombotic conditions. It can be useful in a variety of medical situations, but its use should be done with caution and only under the supervision of specialists.



Defibrinization is the process of removing fibrin from the blood. Fibrin is a blood plasma protein that plays an important role in blood clotting.

Defibrinization is usually performed in a laboratory using a special procedure. Its essence is as follows:

  1. The blood is placed in a test tube and shaken or mixed vigorously. This leads to the activation of fibrinogen (an inactive form of fibrin) and the formation of fibrin threads.

  2. Thin glass or metal wires are then placed into the blood. When shaken, fibrin threads stick to the surface of the wires.

  3. After this, the wires with adhered fibrin are removed from the test tube.

  4. In this way, fibrin is removed and defibrinated blood is obtained, which is no longer able to clot.

Defibrinization is used in laboratory practice when conducting various studies of the composition and properties of blood. In addition, it is sometimes used in medicine as a component of complex treatment of certain diseases associated with bleeding disorders.



Today we will talk about an important procedure - defibrinization, which is the removal of fibrin from the blood. Fibrins are special proteins of the blood coagulation system. They occur in response to damage or dysfunction of the vascular endothelium and lead to its coagulation, which is the main cause of blood clots. However, until the use of anticoagulant drugs, fibrins were an inevitable component of the disease. Therefore, their removal is a difficult task, which is accomplished using a special defibrination procedure. This process is carried out in many laboratories and medical centers around the world.

First of all, it should be noted that defibration is a relatively new direction, introduced in the mid-90s of the last century. Initially, it was applied to the blood of a patient in a state of acute blood loss, as well as in connection with the disease thrombocytopenia. This procedure demonstrates effectiveness in cases where classical anticoagulation therapy is contraindicated. The use of defibrinology is also useful in the treatment of diseases associated with loss of blood clotting (hemolytic anemia), disseminated intravascular coagulation syndrome and major operations after severe vascular damage. When special materials are introduced into the patient's blood, protein compounds such as fibrinogen are captured. These compounds are quite easily removed from the blood due to their abundance and solubility. In this case, the coagulation mechanisms and fibrin systems are simultaneously activated, which makes it possible to quickly compensate for fibrin deficiency and stop bleeding in the patient. Defibrated drugs have a specific composition, which includes various components responsible for their action and rapid stop of bleeding. On the other hand, some experts believe that the use of such a procedure entails a significant possibility of blood transfusion. The fact is that