Deoxyribonuclease

Deoxyribonuclease is an enzyme that breaks down deoxyribonucleic acid (DNA) molecules. It is present in the lysosomes of cells.

Deoxyribonuclease catalyzes the hydrolysis of phosphodiester bonds between deoxyribose and phosphate groups in the DNA molecule. As a result of this process, DNA is split into shorter fragments - nucleotides and oligonucleotides.

Deoxyribonuclease plays an important role in the metabolism of nucleic acids. It is involved in DNA degradation during apoptosis and phagocytosis. In addition, deoxyribonuclease is involved in DNA repair, recombination and replication. Inactivation of this enzyme leads to disruption of these cellular processes.

Thus, deoxyribonuclease is an important enzyme that cleaves DNA and is involved in the regulation of many processes associated with the metabolism of nucleic acids. Its activity is precisely controlled by the cell.

Deoxyribonuclease is an enzyme that is present in the lysosomes of cells and breaks down DNA molecules. Deoxyribonuclease catalyzes the hydrolysis of phosphodiester bonds in the DNA molecule, as a result of which the DNA chain is broken into separate fragments.

There are several types of deoxyribonucleases, which differ in location and function. For example, deoxyribonuclease I is present in the nucleus and is involved in DNA replication and repair. Deoxyribonuclease II is localized in the cytoplasm and destroys damaged nucleic acid fragments.

DNA cleavage by deoxyribonuclease plays an important role in cellular processes such as apoptosis, nucleotide recycling, and preventing the accumulation of excess and damaged DNA in the cell. Inactivation or mutations of deoxyribonuclease genes can lead to disruption of these processes and the development of pathologies.

Deoxynucleases

**Description**: Enzymes that catalyze the breaking of carbohydrate bonds between two nucleosides (monomers) and cleave a chain of nucleotides are called endonucleases. This type of enzyme catalyzes the breaking of three chemical bonds of a chain consisting of four DNA monomer-nucleotide units, cleaves off the methyl groups of the terminal N-glycosides of the last monomers of the molecule, and also serves as a destructive inhibitor of RNA synthesis. The enzyme molecule consists of two subunits, built according to the principle of a quaternary structure, of the “head-anchor” type: this is a structural component of the EMC protein (epsilon motor), and