Dopan belongs to the group of cytostatic drugs - derivatives of bis-(beta-chloroethyl)-amine. Its international name is chloroethylaminouracil.
Dopan has antitumor activity. It alkylates cell DNA, which leads to disruption of replication and transcription processes. This stops cancer cells from dividing.
The drug is used to treat lymphogranulomatosis, lymphosarcoma, breast cancer, ovarian cancer, cervical cancer and other malignant neoplasms.
Dopan is administered intravenously, intramuscularly or orally. It is well absorbed and distributed throughout organs and tissues.
Side effects of dopan include nausea, vomiting, leukopenia, thrombocytopenia. The drug may have a mutagenic and carcinogenic effect.
Thus, dopan is an effective cytostatic agent used to treat various types of cancer. However, when using it, it is necessary to monitor possible side effects.